1.生物医学超声，治疗超声，超声成像及治疗监控

2.生物医学信号获取、处理及仪器

3.机器学习与深度学习

教育经历：

2004.05 获得西安交通大学生物医学工程专业博士学位

1990.05 获得西安交通大学西安交通大学机械电子专业硕士学位

1982.07获得浙江大学测试技术及自动化仪表专业学士学位

工作经历：

1997.5至今 西安交通大学生命科学与技术学院，生物医学影像与应用研究所，生物医学工程系，教授和博士生导师

1990.6-1997.5 西安交通大学材料学院任教

1982.8-1987.8 西安矿业学院任教

主持5项国家自然科学基金面上项目：

1.主持国家自然科学基金面上项目“非线性增效相控阵脉冲超声经颅液化脑出血血肿块治疗及优化方法” （No. 11974274，2020.1～2023.12）

2.主持国家自然科学基金面上项目“增强焦区空化机制的共焦双倍频分裂焦点聚焦超声手术新方法” （No.11674261，2017.1～2020.12）

3.主持国家自然科学基金面上项目“高分辨率空时自适应波控的HIFU损伤声辐射力剪切波粘弹性成像” （No.61372017，2014.1～2017.12）

4.主持国家自然科学基金项目“超声相控阵多焦点、多频调幅辐射力HIFU损伤瞬态响应剪切波成像” (No.3070828, 2010.1-2012.12)

5.主持国家自然科学基金面上项目“相控阵HIFU有效增强焦点处空化及非线性组织损伤机制研究”（No.10674108，2007.1～2009.12）

主要研究论文(Selected Publications)

[1] Yujiao Li, Rui Wang, Mingzhu Lu*, Linglu Zhang, Yanshan Liu, Dan Han, Xuan Wang, Yizhe Geng, and Mingxi Wan, “Histotripsy using dual frequency of second harmonic superimposition and hundred-microsecond ultrasound pulses,” Ultrasound Med Biol ,vol.44, No. 10, pp.2089-2104, 2018

[2] Yujiao Li, Yehui Lu, Rixin Li, Mingzhu Lu*, Xuan Wang, Yizhe Geng Quan Zhang , Mingxi Wan , “Histotripsy liquefaction of large hematoma for intracerebral hemorrhage using millisecond-length ultrasound pulse groups combined with fundamental and second harmonic superposition: a preliminary study,”Ultrasound Med Biol ,vol.46, No. 5, pp.1244-1257, 2020

[3] Xuan Wang, Yizhe Geng, Dan Han, Mingzhu Lu ^* , Ruixin Li, Yujiao Li, Quan Zhang, Mingxi Wan, “Viscoelastic characterization of HIFU ablation with shear wave by using K-Space analysis combined with model-fitting correction method,” Ultrasonics,108:106179 ,2020

[4] Yujiao Li, Weijun Huang, Fengchao MA, Rui Wang, Mingzhu Lu*, Mingxi Wan*, ” A modified Monte Carlo model of speckle tracking of shear wave induced by acoustic radiation force for acousto-optic elasticity imaging,” Chin. Phys. Lett. Vol.33, No. 11, 114301, 2016

[5] Mingzhu Lu, Yu Shi, Li Fang, Yubo Guan, Hujie Jiang, Mingxi Wan, “Enhanced –cavitation heating protocols in focused ultrasound surgery with broadband split-focus approach,” IEEE Trans. Ultrason., Ferroelect., Freq. Contr.Vol.61.No.4,PP:631-646,2014

[6] Yubo Guan, Mingzhu Lu, Zhilong Shen, Mingxi Wan,”Optical tracking of local surface wave for skin viscoelasticity,” Med. Eng. Phys. 36: 708–71, 2014

[7] Mingzhu Lu，Xuejin Liu，Yu Shi，Yanni  Kang，Yubo Guan,  Mingxi Wan，“Propagation of shear waves generated by acoustic radiation force in nondissipative inhomogeneous media” Chin. Phys. Lett., 29(1) 014301, 2012

[8] Mingzhu Lu, Yupeng Wu, Yu Shi，Yubo Guan, Xiaoli Guo，Mingxi Wan, “Monte Carlo Simulation of scattered light with shear waves generated by acoustic radiation force for acousto-optic imaging,” Chin. Phys. Lett. 29(12), 124302, 2012

[9] Mingzhu Lu, Xiaodong Wang, Mingxi Wan, Yi Feng, Feng Xu, Hui Zhong and Jinwen Tan, “Image-guided 256-element ultrasound phased array for noninvasive focused ultrasound surgery,” IEEE Eng. Med. Biol. Mag., vol. 27, No. 5, pp. 84-90, 2008

[10] Mingzhu Lu, Mingxi Wan, Xiaodong Wang,“Optimum protocols in the design of 2-D  spherical-sectioned phased-array for 3-D focused ultrasound surgery,” IEEE Ultrason. Symp.,:662-665, 2008

[12] Mingzhu Lu, Mingxi Wan, Feng Xu, Xiaodong Wang, and Hui Zhong, “Focused beam control for ultrasound surgery with spherical-section phased array: sound field calculation and genetic optimization algorithm,” IEEE Trans. Ultarson., Ferroelect., Freq. Contr., vol. 52, no. 8, pp.1270-1290, 2005

[13] Mingzhu Lu, Mingxi Wan, Feng Xu, Xiaodong Wang，“Design and experiment of 256-element ultrasound phased array for noninvasive focused ultrasound surgery,” Ultrasonics，44: e525-e530，2006