1.肥胖及糖尿病的发病机制；

2. 围产代谢健康。

罗肖，博士，西安交通大学基础医学院生理学与病理生理学系 教授，博士研究生导师。兼任陕西省生理科学会常务理事、陕西省预防医学会营养与食品安全专业委员会委员。

工作至今一直承担医学基础课程《生理学》、《机能实验学》、《高级医学研究英语实践》和医学宗濂班PBL的教学工作。参编人民卫生出版社等配套教材5部。

主要从事肥胖与糖尿病发病机制研究。发表学术论文40余篇，其中在国际高水平学术期刊《Brief Bioinform》、《Diabetes》、《J Nutr Biochem》、《Acta Physiologica》、《Mol Nutr Food Res》、《Mol Cell Endocrinol》等发表论文30余篇。主持国家自然科学基金项3项，中国博士后基金一等1项，中国博士后特别资助1项，陕西省自然科学基金1项，陕西省博士后基金二等1项，中央高校基本科研业务项目2项。指导大学生创新实验项目10项，指导大学生获全国基础医学实验设计大赛铜奖1项。2015年获张锡钧基金会优秀论文奖。

1.DNMT1-NR4A3-UCP1轴调控脂肪组织功能：妊娠期糖尿病子代性别差异性肥胖发生的新机制，2023.1-2026.12，国家自然科学基金项目（82270900），52万元。

2.新的人LncRNA：lnc-GAT1调控妊娠期糖尿病患者脂肪组织慢性炎症反应的分子机制，2019.1-2022.12，国家自然科学基金项目（81871190），57万元。

3.利用基因敲除鼠模型研究BAMBI 基因在脂肪细胞形成中的作用及分子机制，2013.1-2015.12，国家自然科学基金项目（31200886），23万元。

4.BAMBI在脂肪细胞形成中的生理学作用研究，2012.9-2014.9，西安交通大学基本科研业务费 国际科技合作项目（2012jdhz61），4万元。

5.BAMBI缺失对小鼠棕色样脂肪细胞形成的影响及分子机制，2015.7-2017.7，中国博士后科学基金一等（2015M580856），8万元。

6.妊娠期糖尿病患者大网膜脂肪慢性炎症反应中的关键LncRNA功能及其调控机制研究，2016.1-2018.1，西安交通大学基本科研业务费 综合交叉项目(xjj2016089)，10万元。

7.BAMBI在小鼠beige细胞定向与分化过程中的作用研究，2016.1-2017.12，陕西省自然科学基础研究计划-青年人才项目（2016JQ8021），3万元。

8.利用敲除鼠模型研究BAMBI基因在冷刺激诱导皮下脂肪血管生成中的作用及分子机制，2016.7-2017.7，陕西省博士后基金二等（2016BSHEDZZ86），2万元。

9.GDM患者OAT炎症反应中关键LncRNA功能研究，2017.7-2019.7，中国博士后科学基金特别资助（2017T100759），15万元。

代表性论文：

1. Zhao Yang; Jianan Jiang; Yutian Tan; Guiying Yang; Miao Chen; Jiaqi Huang; Jing Liu; Xiaojing Wei; Siyao Wang; Xiao Luo*; Zhen Han*; Sexual dimorphism in thermogenic regulators and metrnl expression in adipose tissue of offspring mice exposed to maternal and postnatal overnutrition. J Physiol Biochem. 2024 Mar 16. doi: 10.1007/s13105-024-01013-2.

2. Xiaojing Wei; Yutian Tan; Jiaqi Huang; Ximing Dong;Weijie Feng;Tanglin Liu; Zhao Yang; Guiying Yang;Xiao Luo*；N1-methylnicotinamide impairs gestational glucose tolerance in mice. J Mol Endocrinol. 2024 Jan 8;72(2):e230126.

3. Yuwei Zhang; Yifei Zhang; Yutian Tan; Xiao Luo*;Ru Jia*；Increased RBP4 and Asprosin Are Novel Contributors in Inflammation Process of Periodontitis in Obese Rats. Int J Mol Sci. 2023 Nov 25;24(23):16739.

4. Xiaojing Wei; Chuanfei Wei; Yutian Tan; Ximing Dong; Zhao Yang; Jianqun Yan; Xiao Luo*; Both prolonged high-fat diet consumption and calorie restriction boost hepatic NAD+ metabolism in mice. J Nutr Biochem. 2023 May;115:109296.

5. Qing Song; Qingying Gao; Taotao Chen; Ting Wen; Peng Wu; Xiao Luo*; Qiaoyi Chen*; FAM3A Ameliorates Brain Impairment Induced by Hypoxia-Ischemia in Neonatal Rat. Cell Mol Neurobiol, 2023 Jan;43(1):251-264. 

6. Chen Shen; Huiyu Li; Miao Li; Yu Niu; Jing Liu; Li Zhu; Hongsheng Gui; Wei Han; Huiying Wang; Wenpei Zhang; Xiaochen Wang; Xiao Luo*; Yu Sun*; Jiangwei Yan*; Fanglin Guan*; DLRAPom: a hybrid pipeline of Optimized XGBoost-guided integrative multiomics analysis for identifying targetable disease-related lncRNA–miRNA–mRNA regulatory axes. Briefings in Bioinformatics. 2022;28(2): bbac046.  

7. Zhao Yang; Jianan Jiang; Miao Chen; Jiaqi Huang; Jing Liu; Xiaojing Wei; Ru Jia; Lin Song; Bo Sun; Xiao Luo*; Qing Song*; Zhen Han*; Sex-Specific Effects of Maternal and Post-Weaning High-Fat Diet on Adipose Tissue Remodeling and Asprosin Expression in Mice Offspring. Mol Nutr Food Res. 2022; 66(4):e2100470.    

8. Ru Jia#; Xiaojing Wei#; Jianan Jiang; Zhao Yang; Jiaqi Huang; Jing Liu; Jianqun Yan; Xiao Luo*; NNMT is induced dynamically during beige adipogenesis in adipose tissues depot-specific manner. J Physiol Biochem. 2022 Feb;78(1):169-183.  

9. Xiaojing Wei; Ru Jia; Zhao Yang; Jianan Jiang; Jiaqi Huang; Jianqun Yan; Xiao Luo*; NAD+/sirtuin metabolism is enhanced in response to cold-induced changes in lipid metabolism in mouse liver. FEBS Lett. 2020 Jun;594(11):1711-1725.  

10. Xiaojing Wei; Ru Jia; Guan Wang; Shangyu Hong; Lin Song; Bo Sun; Ke Chen; Nan Wang; Qiqi Wang; Xiao Luo*; Jianqun Yan*; Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction. J Nutr Biochem. 2020 Jun;80:108377.     

11. Xiao Luo#; Zhangya He#; Xiaomin Sun; Xinqian Gu; Wanyu Zhang; Jiayi Gao; Xiaomin Li; Ru Jia; Junxiang Wei; Yan Yu; Xiaoqin Luo*; DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model. Diabetes Metab Syndr Obes. 2020 22;13:185-196.   

12. Xiao Luo#; Ru Jia#; Xiaoqin Luo; Guan Wang; Qiangling Zhang; Hu Qiao; Nan Wang; Jianqun Yan*; Cold Exposure Differentially Stimulates Angiogenesis in BAT and WAT of Mice: Implication in Adrenergic Activation. Cell Physiol Biochem, 2017;42:974-986 .

13. Xiao Luo#; Ru Jia#; Qianglin Zhang; Bo Sun; Jianqun Yan*; Cold-Induced Browning Dynamically Alters the Expression Profiles of Inflammatory Adipokines with Tissue Specificity in Mice. Int J Mol Sci, 2016;17(5): 795-808.  

14. Xiaoqin Luo; Ru Jia; Qinyu Yao; Yirui Xu; Zhenyu Luo; Xiao Luo*; Nanping Wang*; Docosahexaenoic Acid Attenuates Adipose Tissue Angiogenesis and Insulin Resistance in High Fat Diet-fed Mid-aged Mice via a Sirt1-dependent Mechanism. Molecular Nutrition & Food Research, 2016; 60:871-885 .

15. Ru Jia; Xiaoqin Luo; Guan Wang; Caixia Lin; Hu Qiao; Nan Wang; Ting Yao; Johanna L. Barclay; Jonathan P. Whitehead; Xiao Luo*; Jianqun Yan*; Characterization of cold-induced remodeling reveals depot-specific differences across and within brown and white adipose tissues in mice. Acta Physiologica, 2016; 217(4):311-24. 

16. Xiao Luo; Louise J. Hutley; Julie A. Webster; Yu-Hee Kim; Dong-Fang Liu; Felicity S. Newell; Charlotte H. Widberg; Anthony Bachmann; Nigel Turner; Carsten Schmitz-Peiffer; Johannes B. Prins; Gong-She Yang*; Jonathan P. Whitehead*; Identification of BAMBI as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors. Diabetes, 2012;61(1):124-136 .