李洋 |
1. C-H键官能团化及其在串联反应中应用
2. 过渡金属催化的烯炔官能团化反应
3. 生物活性分子的设计合成
4. 手性催化剂的设计合成与应用
1.国家自然科学基金青年项目,21602167,氮杂环卡宾催化的甲酰基环丙烷[4+n]开环环加成反应研究,2017/01-2019/12,20万元,主持。
2.陕西省自然科学基金青年人才项目 ,2016JQ2019,叔膦催化的缺电子亚甲基环丙烷开环环化反应研究,2016/01-2017/12,4万元。
3.国家自然科学基金面上项目,21871218,Lewis碱催化贫电子环丙烷的开环串联反应及在5/7/6环系紫杉烷二萜天然产物合成中的应用,2019/01-2022/12,65万元,参与。
(1) Yang Li*, Dandan Shi, Xin He, Yongzhuang Wang, Yuhai Tang, Junjie Zhang, Silong Xu*, Redox-Neutral Annulation of Alkynylcyclopropanes with N-Aryloxyamides via Rhodium(III)-Catalyzed Sequential C–H/C–C Activation, The Journal of Organic Chemistry, 2019, 84(3): 1588−1595.
(2) Yang Li*, Silong Xu*, Transition−Metal−Catalyzed C−H Functionalization for Construction of Quaternary Carbon Centers, Chemistry-A European Journal, 2018, 24(61): 16218−16245.
(3) Yang Li*, Dandan Shi, Yuhai Tang, Xin He, Silong Xu*, Rhodium(III)-Catalyzed Redox-Neutral C−H Activation/Annulation of N-Aryloxyacetamides with Alkynyloxiranes: Synthesis of Highly Functionalized 2,3-Dihydrobenzofurans, The Journal of Organic Chemistry, 2018, 83(16): 9464−9470.
(4) Yang Li*, Yuhai Tang, Xin He, Dandan Shi, Jun Wu, Silong Xu*, Rhodium(III)-Catalyzed Annulative Carbooxygenation of 1,1-Disubstituted Alkenes Triggered by C−H Activation, Chemistry-A European Journal, 2017, 23(31): 7453−7457.
(5) Xin He, Yuhai Tang, Yongzhuang Wang, Jian-Bo Chen, Silong Xu,* Jianwei Dou, and Yang Li*, Phosphine-Catalyzed Activation of Alkylidenecyclopropanes: Rearrangement to Form Polysubstituted Furans and Dienones, Angewandte Chemie International Edition, 2019, 58 (31): 10698-10702.
(6) Yang Li, Zhen Wang, Kuiling. Ding*, Minimizing Aryloxy Elimination in RhI-Catalyzed Asymmetric Hydrogenation of β-Aryloxyacrylic Acids using a Mixed-Ligand StrategyCatalyzed Asymmetric Hydrogenation of β-Aryloxyacrylic Acids using a Mixed-Ligand Strategy, Chem. Eur. J., 2015, 21(46):16387-16390.
(7) Yang Li, Zhen Wang, Kuiling Ding*, Rhodium(I)-Catalyzed Enantioselective Hydrogenation of Substituted Acrylic Acids with Sterically Similar β,β-Diaryls, Angew. Chem. Int. Ed., 2013, 52(26):6748-6752.