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杨维娜  
研究领域(方向)

1. 神经系统退行性疾病的发病机制及防治

2. 神经胶质细胞与阿尔茨海默病

个人及工作简历

教育经历:

2008.09——2014.06  西安交通大学人体解剖与组织胚胎学专业  医学博士

2004.09——2007.07  西安交通大学病理学与病理生理学专业 医学硕士

1995.09——2000.07  西安交通大学临床医学专业     医学学士

工作经历:

2016.01——今  西安交通大学医学部基础医学院人体解剖与组织胚胎学系  副教授

2015.11——今   西安交通大学医学部基础医学院生物学专业  博士后

2007.01——2015.12    西安交通大学医学院人体解剖与组织胚胎学系       讲师

2005.07——2007.01    西安交通大学医学院形态中心        讲师

2000.07——2005.06    西安交通大学医学院形态中心        助教

海外经历:

2016.02——2017.07    美国哈佛大学医学院         访问学者

科研项目

近3年主持的科研项目

1. 国家自然科学基金-青年基金项目(项目号:81500928;起止时间:2016.01-2018.12)

2. 陕西省自然科学基础研究计划项目(项目号:2018JM7056;起止时间:2018.01-2019.12)

3. 中国博士后科学基金第10批特别资助项目(项目号:2017T100758;起止时间:2017.10-2019.10)

4. 中国博士后科学基金第59批面上项目一等资助(项目号:2016M590955;起止时间:2016.07-2019.10)

5. 陕西省博士后科研项目第4批面上项目一等资助(项目号:2016BSHYDZZ04;起止时间:2017.10-2019.10)

6. 中央高校基本科研业务费项目(项目号:xjj2015054;起止时间:2015.01-2017.12)

学术及科研成果、专利、论文

代表性科研论文(近5年)

1. Weina Yang, Jianshui Zhang, Lili Shi, Shengfeng Ji, Xiaohua Yang, Wanying Zhai, Hangfan Zong, Yihua Qian. Protective effects of tanshinone IIA on SH-SY5Y cells against oAβ1–42-induced apoptosis due to prevention of endoplasmic reticulum stress. The International Journal of Biochemistry & Cell Biology, 2019,107: 82-91.

2. Kaige Ma, Lv Jia, Xiaodan Hu, Lili Shi, Kewei Chang, Xinlin Chen, Yihua Qian*, Weina Yang*, Qiumin Qu*. The p38 mitogen- activated protein kinase signaling pathway is involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain. The International Journal of Biochemistry & Cell Biology, 2016,76:75-86.(通讯作者)

3. Chang Liu, Youxuan Wu, Shuai Zha, Mengping Liu, Ying Wang, Guangde Yang, Kaige Ma, Yulang Fei, Yaojie Zhang, Xiaodan Hu, Weina Yang*, Yihua Qian*.  Treatment effects of tanshinoneIIA against intracerebroventricular streptozotocin induced memory deficits in mice. Brain Research, 2016,1631:137-146.(通讯作者)

4. Weina Yang, Keige Ma, Yihua Qian, Jianshui Zhang, Gaifeng Feng, Lili Shi, Zhichao Zhang, Zhaohui Liu. Mitogen-activated protein kinase signaling pathways promote low density lipoprotein receptor-related protein 1-mediated beta-amyloid protein internalizetion in primary cortical neurons. The International Journal of Biochemistry & Cell Biology, 2015,64: 252-264.

5. Weina Yang, Keige Ma, Xinlin Chen, Lili Shi, Guojun Bu, Xiaodan Hu, Hua Han,Yong Liu, Yihua Qian. Mitogen-activated protein kinase signaling pathways is involved in regulating α7 nicotinic cetylcholine receptor mediated amyloid- Aβ uptake in SH-SY5Y cells. Neuroscience, 2014,278:276-290.

6. Weina Yang, Lili Shi, Lianji Chen, Bingyi Zhang, Kaige Ma, Yong Liu, Yihua Qian. Protective effects of perindopril on D-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampusof mice. Brain Research Bulletin, 2014, 109:46-53.

7. Weina Yang, Xiaodan Hu, Hua Han, Lili Shi, Gaifeng Feng,Yong Liu,Yihua Qian. The effects of valsartan on cognitive deficits induced by aluminium trichloride and D-galactose in mice. Neurological Research, 2014,36:651-658.

8. Weina Yang, Hua Han, Xiaodan Hu, Gaifeng Feng, Yihua Qian. The effects of perindopril on cognitive impairment induced by D-galactose and aluminum trichloride via inhibition of acetylcholinesterase activity and oxidative stress. Pharmacology, Biochemistry and Behavior, 2013, 114-115;31-36.

9. Weina Yang, Junjian Wang, Lili Shi, Linhua Yu, Yihua Qian, Yong Liu, Weixi Wang, Shaoli Cheng. Podocyte injury and overexpression of vascular endothelial growth factor and transforming growth factor-beta 1 in adriamycin-induced nephropathy in rats. Cytokine, 2012,59:370-376.

联系方式
电子邮箱:wn_yang@mail.xjtu.edu.cn
联系电话:13152079089
个人主页:
联系地址:西安市雁塔西路76号西安交通大学医学部
更新日期:2019-11-14