1、益生菌及其次生代谢产物开发

2、微生态营养、免疫与健康

3、细菌耐药性与食品安全

2002-2007 中国科学院武汉病毒研究所 博士

2007至今 西安交通大学公共卫生学院营养与食品安全系 讲师、副教授、教授

2014   西安交通大学公共卫生学院实验教学中心 主任

2009-2011  美国俄亥俄州立大学食品与环境学院 博士后研究员

2018、2019 西班牙国家科学院食品科学研究所IATA-CSIC 访问学者

2024至今 陕西省营养与食品安全工程研究中心 主任

主要学术兼职：

中国营养学会益生菌益生元与健康分会常务委员

中国营养学会营养与免疫分会常务委员

中国生物物理学会运动与健康分会理事

陕西省营养学会理事

陕西省微生物学会理事

陕西省预防医学会卫生检验专业委员会常务委员

西安市预防医学会卫生检验专业委员会副主任委员

主持国家自然科学基金4项（青年基金1项、面上基金2项，国际交流项目1项），陕西省自然科学基金3项（含面上项目、国际合作项目、重点研发项目各1项），教育部留学回国人员科研基金1项，食品科学与技术国家重点实验室开放基金1项，中国博士后基金1项，西安交大学科交叉项目4项，及多项企业合作研发项目等。

发表学术论文100余篇，其中第一/通讯作者70余篇，授权国家发明专利10项，实用新型专利4项。参编《中国居民膳食营养素参考摄入量》等论著及教材3部。获陕西省高等学校科学研究成果二等奖(第一完成人)、第三届陕西省微生物学会科学技术二等奖(第一完成人)，指导研究生获首届全国研究生学术创新与成果转化大赛银奖2项。

近5年发表文章：

1)       Liu Chenyang, Zhao Huizhen, Qian Junmin, Xiao Mofan, Wang Jinlei, Wang Yaping, Li Xinyu, Han Bei, Bai Zhuanli, Xu Weijun, Suo Aili. Self-evolving hydrogel dressing temporally accelerates infected diabetic wound healing. Advanced Material. 2026, e23302.

2)       Jiayu Feng#, Congyu Zhang#, Yunyang Lu#, Jiale Qin, Wanghong Su, Rui Dong, Huijuan Xi, Haoya Ma, Jia Lv, Yue Cheng, Haifeng Tang*, Bei Han*. Enhanced gastrointestinal stability and therapeutic efficacy of biofilm self-coated Bacillus amyloliquefaciens probiotic in ulcerative colitis. NPJ Science of Food. 2026

3)       Jianhui Mo, Jiale Qin, Jiayu Feng, Wanghong Su, Rui Dong, Chenran Zhang, Shaoru Li, Jia Lv, Ming Zhao, Li Chen, Yue Cheng*, Bei Han*. Multifunctional antihypertensive postbiotic from Bifidobacterium longum subsp. infantis O161 and its novel ACE-inhibitory peptides. Food Chemistry. 2026

4)       Katarzyna M. Maksym, Kinga Kalita-Kurzyńska*, Diane Spatz, Melinda Boss, Maria Carmen Collado, Anna Gonciarz-Dytman, Bei Han, Asma Khalil, Joanna Kozakiewicz, Ernest Kuchar, Karolina Morze, Rebecca Powell, Natalie Shenker, Sławomir Wątroba, Anna L. David, Aleksandra Wesołowska. Development of Lactation and Breast/Chestfeeding Adverse Event Terminology (LaBAET) Through a Delphi Consensus Approach. International Breastfeeding Journal, 2025, 20: 53.

5)       Xinyao Hou#, Jiayu Feng#, Jiale Qin, Jianhui Mo, Rong Yu, Jia Lv, Shaoru Li, Jing Tian, Yue Cheng*, Bei Han*. Development and comparison of antioxidant postbiotics from Bacillus amyloliquefaciens C-1 to alleviate DSS-induced IBD. Probiotics and Antimicrobial Proteins, 2025, 18(2):2382-2396

6)       Xinxin Ma#, Jianhui Mo#, Lu Shi, Yue Cheng, Jiayu Feng, Jiale Qin, Wanghong Su, Jia Lv, Shaoru Li, Qiang Li, Hui Tan*, Bei Han*. Isolation and characterization of Bifidobacterium spp. from breast milk with different human milk oligosaccharides utilization and anti-inflammatory capacity. Food Research International, 2024，196: 115092.

7)       Sijin Jiang#, Jiale Qin#, Lu Shi, Jiayu Feng, Jianhui Mo, Wanghong Su, Yue Cheng, Jia Lv, Qiang Li, Shaoru Li, Lingxia Zeng, Jing Zhou*, Bei Han*.  Association among gestational weight gain, fucosylated human milk oligosaccharides and breast milk microbiota-an evidence in healthy mothers from Northwest China. Journal of Agricultural and Food Chemistry, 2024，72(45):25135-25145.

8)       Yuan Jia#, Hui Tan#, Yue Cheng, Xinxin Ma, Sijin Jiang, Xinyao Hou, Shaoru Li, Lu Shi, Pu Li, Hongmei Xu, Jia Lv, Bei Han*. Air particulate pollution exposure associated with impaired cognition via microbiota gut-brain axis: an evidence from rural elderly female in northwest China. Environmental Science and Pollution Research. 2023,31(4):6398-6410.

9)       Yi Zhou, Yue Cheng, Tianyou Ma, Jun Wang, Shaoru Li, Jingdan Wang, Lei Han, Xinyao Hou, Xinxin Ma, Sijing Jiang, Pu Li, Jia Lv, Bei Han*, Rong Da*.  Transcriptomic and phenotype analysis revealed the role of rpoS in stress resistance and virulence of a novel ST3355 ESBL producing hypervirulent Klebsiella pneumoniae isolate. Frontiers in Cellular and Infection Microbiology. 2023, 13：1259472

10)    Jin Liu, Lu Shi, Xinxin Ma, Sijin Jiang, Xinyao Hou, Pu Li, Yue Cheng, Jia Lv, Shaoru Li, Tianyou Ma*, Bei Han*. Character and antioxidant activity of selenium-enriched probiotic Bacillus amyloliquefaciens C-1, a potential postbiotics. Scientific Reports, 2023, 13(1):14302

11)    Wang Jun#, Ma Xinxin#, Li Jing, Shi Lu, Liu Lijuan, Hou Xinyao, Jiang Sijin, Li Pu, Lv Jia, Han Lei, Cheng Yue, Han Bei*. The synergistic antimicrobial effect and mechanism of Nisin and Oxacillin against Methicillin-Resistant Staphylococcus aureus. International Journal of Molecular Sciences, 2023, 24,6697

12)    Rong Feng, Hongmei Xu*, Hongwei Lu, Bei Han, Yue Cheng, Yunxuan Gu, Jian Sun, Liu Yang, Zhenxing Shen, Junji Cao. Effects of PM2.5 emissions from household fuel combustion on biomarkers and pulmonary function in rural areas of Fenwei Plain, China. Atmospheric Pollution Research. 2023.

13)    Yunxuan Gu, Hongmei Xu, Rong Feng, Yue Cheng, Bei Han, Kin Fai Ho, Zexuan Wang, Yansu He, Linli Qu, Steven Sai Hang Ho, Jian Sun, Zhenxing Shen, Junji Cao. Associations of personal exposure to domestic heating and cooking fuel emissions and epidemiological effects on rural residents in the Fenwei Plain, China. Science of The Total Environment. 2023, 856(2): 159217 (Q1/ IF10.751)

14)    Mireia Valles-Colomer*, Aitor Blanco-Míguez, Paolo Manghi, Francesco Asnicar, Leonard Dubois, Davide Golzato, Federica Armanini, Fabio Cumbo, Kun D Huang, Serena Manara, Giulia Masetti, Federica Pinto, Elisa Piperni, Michal Punčochář, Liviana Ricci, Moreno Zolfo, Olivia Farrant, Adriana Goncalves, Marta Selma-Royo, Ana G Binetti, Jimmy E Becerra, Bei Han, John Lusingu, John Amuasi, Loredana Amoroso, Alessia Visconti, Claire M Steves, Mario Falchi, Michele Filosi, Adrian Tett, Anna Last, Qian Xu, Nan Qin, Huanlong Qin, Jürgen May, Daniel Eibach, Maria Valeria Corrias, Mirco Ponzoni, Edoardo Pasolli, Tim D Spector, Enrico Domenici, Maria Carmen Collado, Nicola Segata*. The person-to-person transmission landscape of the gut and oral microbiomes. Nature, 2023. 614(7946):125-135. ESI高被引用文章 0.1%热点论文

15)    Lijuan Liu, Lu Shi, Pu Li, Xinxin Ma, Xinyao Hou, Sijin Jiang, Jia Lv, Hongmei Xu, Yue Cheng, Bei Han*. Seasonal dynamics survey and association analysis of microbiota communities, antibiotic resistance genes distribution and biotoxicities characterization in landfill-leachate. Ecotoxicology and Environmental Safety. 2022, 245:114103

16)    Jin Liu#, Lu Shi#, Xiaohong Tuo, Xinxin Ma, Xinyao Hou, Sijin Jiang, Jia Lv, Yue Cheng, Dagang Guo, Bei Han*. Preparation, characteristic and anti-inflammatory effect of selenium nanoparticle-enriched probiotic strain Enterococcus durans A8-1. Journal of Trace Elements in Medicine and Biology. 2022,74:127056

17)    Jia Yuan, Lu Shi, Hongbo Li, Jing Zhou, Lingxia Zeng, Yue Cheng*, Bei Han*. The burden of neonatal diseases attributable to ambient PM 2.5 in China from 1990 to 2019. Frontiers in Environmental Science, 2022, 10: 828408.

18)    Yue Cheng#, Marta Selma-Royo#, Xin Cao, Marta Calatayud, Qi Qi, Jing Zhou, Lingxia Zeng, Izaskun García-Mantrana, Maria Carmen Collado*, Bei Han*. Influence of geographical location on Maternal-infant microbiota: study in two populations from Asia and Europe. Frontiers in Cellular and Infection Microbiology. 2022, 11: 663513.

HongBao Li#*, MengLu Xu#, XuDong Xu#, YuYan Tang#, HongLi Jiang, Lu Li, WenJie Xia, Nan Cui, Juan Bai, ZhiMing Dai, Bei Han, Ying Li, Bo Peng, YuanYuan Dong, Sachin Aryal, Ishan Manandhar, Mahmoud Ali Eladawi, Rammohan Shukla, YuMing Kang*, Bina Joe*, Tao Yang*. Faecalibacterium prausnitzii Attenuates CKD via Butyrate-Renal GPR43 Axis. Circulation Research, 2022, 131:e120-e134