杨健 |
(1)脑发育与脑损伤的影像研究;
(2)磁共振功能与分子成像;
(3)脑肿瘤的影像学研究;
(4)心血管疾病影像研究。
分别于1993年、1998年毕业于原西安医科大学,获临床医学学士和影像医学硕士学位,导师:杨广夫教授。2004年毕业于西安交通大学生命科学与技术学院,获生物医学工程博士学位,导师万明习教授。2005年-2007年于香港大学电子电气工程学院BISP-7T MRI中心从事博士后研究, 导师吴学奎教授。
1.主持2017年国家自然科学基金,局灶性白质损伤患儿脑微结构隐性病变的早期MRI个体化评估,No.81771810,获资助55万元。
2.主持2016年国家重点研发计划数字诊疗装备研发专项前沿和共性技术创新:新生儿局灶性白质损伤预后评估的磁共振成像新技术集成及其临床应用。 No:2016YFC0100300, 获资助340万元
3.主持2014年国家自然科学基金,非低出生体重早产儿脑结构及其网络的纵向MRI研究 No: 81471631,获资助73万元。
4.主持2012年国家自然科学基金,新生儿缺血缺氧脑病的磁共振扩散峰度成像新技术研究. No: 81171317,获资助58万元。
5.主持2010年国家自然科学基金,“大鼠脑室下区内源性神经干/祖细胞的MR 活体示踪研究” NO:30970797, 获资助33万元。
6.主持2002年国家自然科学基金,“磁共振的肺功能成像技术和图像后处理研究”,NO:30200066,获资助21万元。
7.主持2011年教育部新世纪优秀人才支持计划项目名称:新生儿缺血缺氧脑病的多模态磁共振成像研究。No: NCET-11-0438获资助50万元
1. Chao Jin ,Yanyan Li ,Xianjun Li ,Miaomiao Wang ,Congcong Liu, Jie Gao ,Qinli Sun ,Deqiang Qiu, Lingxia Zeng, Xihui Zhou,Gailian Li, Jinni Zhang, Jie Zheng ,Jian Yang*.Proper timing for the evaluation of neonatal brain white matter: a diffusion tensor imaging study. European Radiology. In press
2. Yannan Cheng, Heng Liu, Chenxia Li, Chao Jin, Huifang Zhao, Xiaoyu Wang, Xingxing Tao, Jian Yang*. Clinical and Radiological features of peripancreatic/ pancreatic Castleman disease: case report and literature review. Int J Clin Exp Med. In press
3. Miaomiao Wang, Heng Liu, Xiaocheng Wei, Congcong Liu, Ting Liang, Xianghui Zhang, Chao Jin, Xianjun Li, Qinli Sun, Haoxiang Jiang, Jian Yang*. Application of Reduced Field-of-View Diffusion-Weighted Imaging in Evaluation of Normal Pituitary Glands and Pituitary Macroadenomas. American Journal of Neuroradiology, 2018. In Press
4. Xinxin Liu, Hua Li, Chao Jin, Gang Niu, Baoqin Guo, Yi Chen, Jian Yang*. Differentiation Between Brucellar and Tuberculous Spondylodiscitis in the Acute and Subacute Stages by MRI:A Retrospective Observational Study. Acad Radiol 2018 https://doi.org/10.1016/j.acra.2018.01.028
5. Xiaoling Zhang, Jie Gao, Feng Zhu, Wei Wang, Yajuan Fan, Qingyan Ma, Xiancang Ma, Jian Yang*. Reduced white matter connectivity associated with auditory verbal hallucinations in first-episode and chronic schizophrenia: A diffusion tensor imaging study.Psychiatry Research: Neuroimaging 273 (2018) 63–70
6. Cailei Zhao, Qian Chen,Chunde Li, Jian Yang*, Cong Li, Yangyang Zhou, Jianxiang Liao.The association of NF2 (neurofibromin 2) gene polymorphism and the risk of medulloblastomas.Neurological Sciences.2018 https://doi.org/10.1007/ s10072-018-3327-0
7. Chao Jin, Huan Li, Xianjun Li, Miaomiao Wang, Congcong Liu, Jianxin Guo, Jian Yang*. Temporary hearing threshold shift in healthy volunteers with hearing protection caused by acoustic noise exposure during 3-T multisequence MR neuroimaging. Radiology. 2018 Feb;286(2):602-608. doi: 10.1148/radiol.2017161622. Epub 2017 Aug 16
8. Zhiqiang Chen, Yi Zheng, Guanghai Ji, Xinxin Liu, Peng Li, Lei Cai, Yulin
Guo and Jian Yang* Accuracy of dynamic contrast-enhanced magnetic resonance imaging in the diagnosis of prostate cancer: systematic review and meta-analysis. Oncotarget, 2017, 8(44):77975-77989
9. Heng Liu, Ting Liang, Jie Lian, Miaomiao Wang, Congcong Liu, Xiaoyu Wang, Jian Yang*. Clinical and CT features of adrenal cystic lymphangioma: case series and literature review. Int J Clin Exp Med 2017;10(5):8472-8480
10. Shun Qi, Yun-Feng Mu, Long-Biao Cui, Jian Zhang, Fan Guo,Qing-Rong Tan,Mei Shi, Kang Liu, Yi-Bin Xi,Nan-Yin Zhang, Xiao-Liang Zhang, Yong He, Jian Yang*, Hong Yin*. Anomalous gray matter structural networks in recent onset post-traumatic stress disorder. Brain Imaging and Behavior 2017 DOI 10.1007/s11682-017-9693-z
11. Xianjun Li, Jie Gao, Miaomiao Wang, Yanyan Li, Edward S. Hui, Mingxi Wan, Jian Yang*. Characterization of Extensive Microstructural Variations Associated with Punctate White Matter Lesions in Preterm Neonates. American Journal of Neuroradiology, June 2017, 38 (6) 1228-1234
12. Jie Gao, Xianjun Li, Yanyan Li, Lingxia Zeng, Chao Jin, Qinli Sun, Duan Xu, BolangYu, Jian Yang*. Differentiating T2 hyperintensity in neonatal white matter by two-compartment model of diffusional kurtosis imaging. Scientific Reports, 2016, 6:24473 | DOI: 10.1038/srep24473 (IF: 5.578)
13. Shun Qi, Yunfeng Mu, Longbiao Cui, Rong Li, Mei Shi, Ying Liu, Junqing Xu, Jian Zhang, Jian Yang*, Hong Yin*. Association of optic radiation integrity with cortical thickness in children with anisometropic amblyopia. Neuroscience bulletin. 2016, 32(1):51–60 (IF: 2.51)
14. Xiaoping Wu, Pan Lin, Junle Yang, Hao Song, Rui Yang,Jian Yang*. Dysfunction of the cingulo-opercular network in first-episode medication-naive patients with major depressive disorder. Journal of Affective Disorders.2016;200:275-83 (IF: 3.38)
15. Xianjun Li, Jie Gao, Miaomiao Wang, Mingxi Wan*, Jian Yang* .Rapid and Reliable Tract-based Spatial Statistics Pipeline for Diffusion Tensor Imaging in the Neonatal Brain: Applications to the White Matter Development and Lesions. Magnetic Resonance Imaging. 2016 Nov;34(9):1314-1321 (IF:2.09)
16. Weishan Zhang, Ning Ning, Xianjun Li, Gang Niu, Lijun Bai, Youmin Guo, Jian Yang*. Changes of Brain Glucose Metabolism in the Pretreatment Patients with Non-Small Cell Lung Cancer: A Retrospective PET/CT Study. PloS one.2016,11(8): e0161325 (IF:3.075)
17. Cailei Zhao, Yongxin Li, Weiguo Cao, Kui Xiang, Heye Zhang, Jian Yang*, Yungen Gan. Diffusion tensor imaging detects early brain microstructure changes before and after ventriculoperitoneal shunt in children with high intracranial pressure hydrocephalus. Medicine (2016) 95:42(e5063) (IF:2.133)
18. Jie Gao, Qinli Sun, Yumiao Zhang, Yanyan Li, Huan Li, Xin Hou, Bolang Yu, Xihui Zhou, Jian Yang*. Semi-quantitative assessment of brain maturation by conventional magnetic resonance imaging in neonates with clinically mild hypoxic-ischemic encephalopathy. Chinese medical journal.2015,128 (5) :p574-580. (IF:1.053)
19. Rong Wang, Jiaqi Ma, Gang Niu, Jie Zheng, Zhe Liu, Yonghao Du, Bolang Yu, Jian Yang*. Differentiation between solitary cerebral metastasis and astrocytoma on the basis of subventricular zone involvement on magnetic resonance imaging. PloS one. 2015,10(7): e0133480. (IF:3.234)
20. Xiang Li, Chenxia Li, Rong Wang, Juan Ren, Jian Yang*, Yuelang Zhang*. Combined application of gadoxetic acid disodium-enhanced magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) in the diagnosis of chronic liver lisease-induced hepatocellular carcinoma: a meta-analysis. PloS one. 2015,10(12):e0144247. (IF:3.234)
21. Cailei Zhao, Jian Yang*, Yungen Gan, Jiangang Liu, Zhen Tan, Guohua Liang, Xianlei Meng, Longwei Sun, Weiguo Cao. Application of MR virtual endoscopy in children with hydrocephalus. Magnetic Resonance Imaging. 2015,33(10):p1205–1211. (IF:2.09)
22. Ning Ning, Lei Zhang, Jie Gao, Yumiao Zhang, Zhuanqin Ren, Gang Niu, Yongming Dai, Ed X. Wu, Youmin Guo, Jian Yang*. Assessment of Iron Deposition and White Matter Maturation in Infant Brains by Using Enhanced T2 Star Weighted Angiography (ESWAN): R2* versus Phase Values. Plos One, 2014, 9 (2),e89888 (IF:3.8)
23. Xianjun Li , Jian Yang*, Jie Gao, Xue Luo, Zhenyu Zhou, Yajie Hu, Ed X. Wu, and Mingxi Wan*. A Robust Post-processing Workflow for Datasets with Motion Artifacts in Diffusion Kurtosis Imaging. Plos One,2014, 9 (4) (IF:3.8)
24. Kevin C. Chan, Joe S. Cheng, Shujuan Fan, Iris Y. Zhou, Jian Yang*, Ed X. Wu*. In vivo evaluation of retinal and callosal projections in early postnatal development and plasticity using manganese-enhanced MRI and diffusion tensor imaging. Neuroimage. 2012 Feb 1;59(3):2274-83 (IF: 6.252)
25. Gang Niu, Jian Yang*, Rong Wang, Ed X. Wu, Youmin GUO. MR assessment of lumbar intervertebral disc degeneration and age-related changes: apparent diffusion coefficient versus T2 quantitation. American Journal of Neuroradiology,2011, 32,1617-1623 (IF:3.464, 共同第一)
26. Runyang Mo, Jian Yang*, Ed.X. Wu, Shuyu Lin.Instant magnetic labeling of tumor cells by ultrasound in vitro. Journal of Magnetism and Magnetic Materials.2011, 323;2287–2294 (IF:1.690)
27. Dengfeng Gao, Ning Ning, Youmin Guo,Wende Ning, Xiaolin Niu, Jian Yang*. Computed tomography for detecting coronary artery plaques: A meta-analysis. Atherosclerosis , 2011.219(2):603-9. (IF:4.086)
28. Yang J, Liu J, Niu G, Chan KC, Wang R, Liu Y, Wu EX. In vivo MRI of endogenous stem/progenitor cell migration from subventricular zone in normal and injured developing brains. Neuroimage. 2009;48(2):319-28. (IF:5.739)
29. J Yang, W Wang, YR Wang, G Niu, CW Jin, EX Wu: A Free-breathing Non-contrast-enhanced Pulmonary Magnetic Resonance Angiography at 3 Tesla. Chinese medical journal, 2009:122:33-38 (IF:0.952)
30. J Yang, EX Wu. Manganese-enhanced MRI detection of gray matter lesion in late phase of mild neonatal hypoxic-ischemic injury. NeuroImage, 2008, 39: 669-679. (IF:5.739)
31. J Yang, Y Wang, AC Chu, SL Ho, PT Cheung, PL Khong, EX Wu: Manganese-enhanced MRI detection of neurodegeneration in neonatal hypoxic-ischemic cerebral injury. Magnetic Resonance in Medicine, 2008,59(6), 1329-39. (IF:3.449)
32. YANG Jian, WAN Mingxi*,GUO Youmin. Pulmonary Magnetic Resonance Functional Imaging: Ventilation-Perfusion with Animal Models,Chinese medical journal 2004,117(10):1489-1496.(IF:0.63)
专利
1.杨健,李贤军,孙亲利,牛刚,高洁,张育苗,胡亚杰,罗雪. 一种扩散磁共振成像运动伪影的消除方. 发明专利号: 201410604514.8
2.杨健,牛刚,李贤军,王蓉,孙亲利,郭建新,荐志洁.磁化转移联合层面选择反转恢复预脉冲的磁共振成像方法. 发明专利, 专利申请号:201510324898.2
3.杨健,李欢,金超,郭建新,王苗苗,李贤军. 一种应用于磁共振设备中的隔音装置. 实用新型专利, 专利申请号:2015205313318