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屈秋民  
研究领域(方向)
认知障碍及帕金森病。
个人及工作简历

1981.09-1986.06 西安医科大学医疗系本科学习

1986.06-1993.05 西安医科大学第一附属医院神经内科住院医师

1993.06-1997.09 西安医科大学第一附属医院神经内科主治医师

1996.06-1997.06 日本医科大学第二内科研修

1997.10-2005.12 西安交通大学第一附属医院神经内科副主任医师

1998.09-2002.10 西安交通大学第一附属医院神经内科在职研究生

2002.10-2004.03 日本北海道大学医学部攻读博士学位

2005.02-2006.03 美国加州大学洛杉矶分校(UCLA)博士后研究

2006.01-至今    西安交通大学第一附属医院神经内科主任医师

2010.12-至今    西安交通大学第一附属医院神经内科教授

科研项目

1.陕西省重点研发计划(No.2018ZDXM-SF-052):西安市农村中老年人认知功能障碍队列研究,2018/07/01—2021/06/30,在研,主持人:屈秋民

2.国家自然科学基金面上项目(No.81771168):糖尿病引起AQP4错位分布的分子机制及其对Aβ清除的影响,2018/01/01—2021/12/31,在研,主持人:屈秋民

3.国家自然科学基金青年项目(No.81700736):糖尿病影响自噬体与溶酶体的融合减弱Aβ清除的分子机制,2018/01/01-2020/12/31,在研,主持人:马楼艳

4.国家重点研发计划“重大慢性非传染性疾病防控研究(No.2017YFC1310103):AD 痴呆前阶段的新药和疗效评价体系研究,2018/01-2020/12,在研,主持人:屈秋民

5.国家重点研发计划“重大慢性非传染性疾病防控研究(No.2016YFC1306305):阿尔茨海默病早期诊断和预警的综合诊断指标体系研究,2017/07—2020/12,在研,主持人:屈秋民

6.石药集团恩必普药业有限公司横向课题:多奈哌齐联合丁苯酞治疗对轻-中度阿尔茨海默病认知功能衰退的影响,2016/01-2018/12,主持人:屈秋民

7.石药集团恩必普药业有限公司横向课题:多奈哌齐联合丁苯酞治疗对轻-中度阿尔茨海默病患者脑葡萄糖代谢及β淀粉样蛋白沉积的影响:一项为期 48 周的随机病例对照研究,2018/03-2019/12,主持人:屈秋民

8.上海绿谷制药有限公司横向课题:阿尔茨海默病患者脑内β淀粉样蛋白沉积与认知功能衰退的关系研究,2016/01-2017/12,主持人:屈秋民

9.齐鲁制药有限公司横向课题:艾地苯醌对轻度阿尔茨海默病患者脑葡萄糖代谢的影响——一项为期12周的随机、双盲、安慰剂对照研究,2018/08-2019/12,主持人:屈秋民

学术及科研成果、专利、论文

1.Ling Gao, Yu Jiang, Shan Wei, Suhang Shang, Pei Li, Chen Chen, Liangjun Dang, Jin Wang, Kang Huo, Meiying Deng, Jingyi Wang, Rong Zhang, Qiumin Qu. The level of plasma amyloid-β40 is correlated with peripheral transport proteins in cognitively normal adults: a population-based cross-sectional study. J Alzheimers Dis.Accepted.

2.Meng Zhang, Yong-Ning Deng, Jing-Yi Zhang, Jie Liu, Yan-Bo Li, Hua Su, Qiu-Min Qu. SIRT3 Protects Rotenone-induced Injury in SH-SY5Y Cells by Promoting Autophagy through the LKB1-AMPK-mTOR Pathway. Aging and Disease.2018; 9(2):273-286.(通讯作者)

3.Hongmei Cao, Jie Shi, Bingqing Cao, Bei Kang, Ming Zhang, Qiumin Qu. Evaluation of the Braak staging of brain pathology with 1H-MRS in patients with Parkinson’s disease. Neuroscience Letters. 2017; 660: 57-62.

4.Yong-Ning Deng, Jun-Yan Zeng, Hua Su, Qiu-Min Qu. Recombinant VLP-Z of JC Polyomavirus: A Novel Vector for Targeting Gene Delivery. Intervirology 2015;58:363–368.(通讯作者)

5.Zhang JY, Deng YN, Zhang M, Su H, Qu QM. SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model. Neurochem Res. 2016; 41(7): 1761-73

6.Wang J, Qiao F, Shang S, Li P, Chen C, Dang L, Jiang Y, Huo K, Deng M, Wang J, Qu Q. Elevation of Plasma Amyloid-β Level is More Significant in Early Stage of Cognitive Impairment: A Population-Based Cross-Sectional Study. J Alzheimers Dis. 2018;64(1):61-69.(通讯作者)

7.Jiang Y, Shang S, Li P, Chen C, Dang L, Wang J, Huo K, Deng M, Wang J, Qu Q. Pulse pressure is associated with plasma amyloid-β transport dysfunction. J Hypertens. 2018; 36(3): 569-79. (通讯作者)

8.Shang S, Li P, Deng M, Jiang Y, Chen C, Qu Q. The Age-Dependent Relationship between Blood Pressure and Cognitive Impairment: A Cross-Sectional Study in a Rural Area of Xi'an, China. PLoS One. 2016 Jul 20;11(7):e0159485. (通讯作者)

9.Fei YL, Lv HJ, Li YB, Liu J, Qian YH, Yang WN, Ma KG, Li HB, Qu QM. Tongxinluo improves the cognition by reducing β-amyloid accumulation in spontaneous hypertensive rats. Brain Res. 2017; 1663: 151-160. (通讯作者)

10.Li Y, Shang S, Fei Y, Chen C, Jiang Y, Dang L, Liu J, Ma L, Wei M, Qu Q. Interactive relations of type 2 diabetes and abdominal obesity to cognitive impairment: A cross-sectional study in rural area of Xi'an in China. J Diabetes Complications. 2018; 32(1): 48-55. (通讯作者)

11.Liu J, Shang S, Li P, Deng M, Chen C, Jiang Y, Dang L, Qu Q. Association between current smoking and cognitive impairment depends on age: A cross-sectional study in Xi'an, China. Med Clin (Barc). 2017; 149(5): 203-8. (通讯作者)

12.Ma LY, Lv YL, Huo K, Liu J, Shang SH, Fei YL, Li YB, Zhao BY, Wei M, Deng YN, Qu QM. Autophagy-lysosome dysfunction is involved in Aβ deposition in STZ-induced diabetic rats. Behav Brain Res. 2017; 320: 484-93. (通讯作者)

13.Lou-Yan Ma, Yu-Lang Fei, Xiao-Ye Wang, Song-Di Wu, Jun-Hui Du, Mei Zhu, Long Jin, Ming Li, Hai-Long Li, Jia-Jia Zhai, Lu-Peng Ji, Ran-Ran Ma, Song-Fang Liu, Mo Li, Li Ma1, Xiao-Rui Ma, Qiu-Min Qu, Ya-Li Lv. The Research on the Relationship of RAGE, LRP-1, and Aβ Accumulation in the Hippocampus, Prefrontal Lobe, and Amygdala of STZ-Induced Diabetic Rats. J Mol Neurosci. 2017; 62:1-10.(通讯作者)

14.Wei M, Zhao B, Huo K, Deng Y, Shang S, Liu J, Li Y, Ma L, Jiang Y, Dang L, Chen C, Wei S, Zhang J, Yang H, Gao F, Qu Q. Sleep Deprivation Induced Plasma Amyloid-β Transport Disturbance in Healthy Young Adults. J Alzheimers Dis. 2017; 57(3): 899-906.(通讯作者)

15.Ma KG, Lv J, Hu XD, Shi LL, Chang KW, Chen XL, Qian YH, Yang WN, Qu QM. The p38 mitogen-activated protein kinase signaling pathway is involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain. Int J Biochem Cell Biol. 2016;76:75-86.(通讯作者)

联系方式
电子邮箱:quqiumin@126.com
联系电话:13892898562
个人主页:
联系地址:西安交通大学第一附属医院神经内科
更新日期:2018-08-08