主要聚焦于聚集诱导发光（AIE）材料，致力于将其发展为高效光催化剂，并推动在生物医药领域的转化应用。目前系统开展以下几个方面的研究：

1. 光催化调控生物体系的氧化还原平衡

2. 光/声敏剂激发态调控与机制解析

3. 可穿戴诊疗分析设备的开发

4. 高灵敏AIE荧光探针的开发及药物评估与示踪

5.研究贯穿“分子设计—机制解析—生物应用—疗效评估”全链条，旨在开发新一代智能诊疗一体化系统，并拓展至药物示踪、智能传感等前沿应用场景。

2021年毕业于西安交通大学前沿科学技术研究院，导师：何刚教授，合作导师：郭保林教授。

2021年至2025年，先后于香港中文大学（深圳）及香港科技大学从事博士后研究，合作导师：唐本忠院士。

2024年3月，入选西安交通大学“青年拔尖人才计划”。

2025年10月，以副教授、博导身份加入西安交通大学药学院。

主持国家自然科学基金项目、粤港澳青年项目、广东省重点实验室开放课题、陕西省校招共用项目；参加深圳市重点实验室筹建启动项目等。

围绕高催化活性AIE光敏剂的开发及其在智能诊疗设备中的市场化应用，取得多项成果。迄今在国际高水平期刊共发表论文28篇，其中以第一作者（含共同一作）及通讯作者身份发表论文16篇，包括Matter, Nature Communications, Angewandte Chemie International Edition, ACS Nano, Advanced Science, Small等；获授权国家专利5项。目前已完成一项智能光动力诊疗设备的开发，样机已制备完成，相关专利已提交申请。

代表性论文：

1) Tang, N. Y. B.; Wang, S.; Xu, L.; Zhou, K.;* Zhao, Z.;* Tang, B. Z.* Aggregation-Induced Emission: Past, Present, and Future. Acc. Chem. Res. 2026, 59, 1297.

2) Wang, W.; Liu, Z.; Li, M.; Zheng, J.; Zhang, R.; Liu, K.; Li, X.; Wen, S.; Yu, J.; Pan, M.; Ma, F.; Zhou, K.;* Zhao, Z.;* Shen, C.;* Liao, Y.,* AIEgen-Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control. Adv. Sci. 2026, 13, e15865.

3) Lyu, X.; Wang, S. Y.; Ye, Z. Y.; Li, Z. J.; Kwok, R. T. K.; Zhou, K.;* Zhao, Z.;* Tang, B. Z.* Subcellular Aggregation of Photosensitizers Overrides Reactive Oxygen Species Generation in Photodynamic Therapy Effects. Small Structures 2026, 7, e202500716.

4) Ma, W.; Ding, R.; Wang, S.; Wang, Z.; Xu, L.; Zhou, K.*; Ma, J.*; He, G.*, On-Site Visualized Periodontitis Screening via Dual-Signal H2S Probe. Adv Healthc. Mater. 2025, e02710. ( Cover Paper)

5) Cheng, Y.; Zhou, K.†; Chen, Y.; Mei, Y.; Wang, Z.; Wang, W. J.; Li, H.; Chen, Y.; Liu, Z.; Zeng, J.; Luo, Y.; He, D.; Zhao, Z.*; Tang, B. Z.*, Concurrent Ferroptosis and Pyroptosis Induced by a Dual-Organelle-Targeted Type I/II AIE Photosensitizer for Bladder Cancer Immunotherapy. Angew. Chem., Int. Ed. 2025, 64, e202509783.

6) Zhou, K., Du, L., Ding, R., Xu L., Shi, S., Wang, S., Wang, Z., Zhang, G., He, G.,* Zhao, Z.,* Tang, B. Z.* Photocatalytic therapy via photoinduced redox imbalance in biological system Nat. Commun. 2024, 15, 10551.

7) Zhou, K.; Yu, Y.; Xu, L.; Wang, S.; Li, Z.; Liu, Y.; Kwok, R. T. K.; Sun, J.; Lam, J. W. Y.; He, G.,* Zhao, Z.,* Tang, B. Z.* Aggregation-Induced Emission Luminogen Based Wearable Visible-Light Penetrator for Deep Photodynamic Therapy. ACS Nano 2024, 18, 29930.

8) Zhou, K., Wang, S., Xu L., Li, H., Wang, Y., Qiu, Z., Zhang, G., Zhao, Z.,* Tang, B. Z.* AIEgen-based smart system for fungal-infected wound monitoring and on-demand photodynamic therapy. Matter 2023, 6, 3449.

9) Zhou, K.; Chigan, D.; Xu, L.; Liu, C.; Ding, R.; Li, G.; Zhang, Z.; Pei, D.; Li, A.; Guo, B.; Yan, X.; He, G*. Anti-Sandwich Structured Photo-Electronic Wound Dressing for Highly Efficient Bacterial Infection Therapy. Small 2021, 17, e2101858.

10) Zhou, K.; Qiu, X.; Xu, L.; Li, G.; Rao, B.; Guo, B.; Pei, D.; Li, A.; He, G*., Poly(selenoviologen) Assembled Upconversion Nanoparticles for Low Power Single NIR Light Triggered Synergistic Photodynamic and Photothermal Antibacterial Therapy. ACS Appl. Mater. Interfaces 2020, 12, 26432.

11) Zhou, K.; Tian, R.; Li, G.; Qiu, X.; Xu, L.; Guo, M.; Chigan, D.; Zhang, Y.; Chen, X.; He, G.*, Cationic Chalcogenoviologen Derivatives for Photodynamic Antimicrobial Therapy and Skin Regeneration. Chem. Eur. J. 2019, 25, 13472. (Cover Paper)

12) Li, G.†; Zhou, K.†; Sun, Q.; Ma, W.; Liu, X.; Zhang, X.; Zhang, L.; Rao, B.; He, Y. L.; He, G.*, Bacteria-Triggered Solar Hydrogen Production via Platinum(II)-Tethered Chalcogenoviologens. Angew. Chem., Int. Ed. 2022, 61, e202115298. (co-first author)

13) Xu, L.; Zhou, K.; Ma, H.; Lv, A.; Pei, D.; Li, G.; Zhang, Y.; An, Z.; Li, A.; He, G.*, Ultralong Organic Phosphorescent Nanocrystals with Long-Lived Triplet Excited States for Afterglow Imaging and Photodynamic Therapy. ACS Appl. Mater. Interfaces 2020, 12, 18385.( co-first author)

14) Xu, L. †; Zhou, K. †; Qiu, X.; Rao, B.; Pei, D.; Li, A.; An, Z.; He, G.*, Tunable ultralong organic phosphorescence modulated by main-group elements with different Lewis acidity and basicity. J. Mater. Chem. C 2020, 8, 14740. (Cover Paper, co-first author)

15) Wang, S.†; Zhou, K.†; Lyu, X.; Li, H.; Qiu, Z.*; Zhao, Z.*; Tang, B. Z.*, The Bioimaging Story of AIEgens. Chemical & Biomedical Imaging 2023, 1, 509. (Cover Paper, co-first author)

16) Lyu, X.; Hu, Y.; Shi, S.; Wang, S.; Li, H.; Wang, Y.; Zhou, K.*, Hydrogel Bioelectronics for Health Monitoring. Biosensors 2023, 13, 815. (corresponding author)

17) Zhang, W.; Feng, X.; Zhang, C.; Jia, Q.; Liu, X.; Zhou, K.*, Activity of N–H in phenothiazine derivatives: synthesis and applications in fluoride ions sensing and electrochromism. J. Mater. Chem. C 2023, 11, 2949. (corresponding author)

18)Zhang, C.; Wang, Z.; Chen, T.; Tang, M.; Zhang, J.; Jian, J.; Wang, Y.; Zhou, K.*; Zhang, X.*, Methylamine Gas Sensor Based on Fluorescent Perovskite Nanocrystal Nanofibers Incorporating Aggregation-Induced Emission Materials. ACS Applied Nano Materials 2024, 7, 17329. (corresponding author)